Adams and Victor’s Principles of Neurology 11th Edition
Adams and Victor’s Principles of Neurology is truly the classic text in its discipline — a celebrated volume that guides clinicians to an in-depth understanding of the key aspects of neurologic disease, including both clinical and new scientific data. This meticulously revised and updated text remains the masterwork in its field, and the most readable reference available. Within its pages, you will find a disciplined presentation of clinical data and lucid descriptions of underlying disease processes.
Some of the features that have made this resource so renowned:
- The most cohesive and consistent approach to clinical management – acclaimed as the most readable book in the literature
- A scholarly approach that gives readers a comprehensive overview of every neurologic illness
- Unmatched coverage of signs and symptoms
- A focus on the full range of therapeutic options available to treat neurologic diseases, including drug therapy and rehabilitation methods
- Coverage of the most exciting discoveries and hypotheses of modern neuroscience that bear on and explain neurologic disease
- Puts the latest scientific discovery into a larger clinical context
- An evenness of style and a uniform approach to subject matter across disciplines that allows a quick and easy review of each topic and condition
- A rich, full-color presentation that includes many high-quality illustrations
The Eleventh Edition is enhanced by new coverage of :
- Interventional therapies for acute ischemic stroke
- Novel immunotherapies used to treat inflammatory and neoplastic conditions, and neurotoxicities associated with these drugs
- New drugs to treat epilepsy and multiple sclerosis
- Update of the genetics of inherited metabolic disease
- Current understanding of the genetics of primary nervous system malignancies and their bearing on treatment.
The definitive guide to understanding, diagnosing and treating neurologic disease – more complete, timely, and essential than ever
A Doody’s Core Title for 2021!
Preface from the ebook:
We are very pleased to bring you the 11th edition of Adams and Victor’s Principles of Neurology. To provide the context for the continued importance and relevance of a textbook that aspires to such breadth and depth, it may be compelling to review a patient’s story; an event that took place between the last edition of this book and this one. Neurologists have always been particularly attracted to the case history as a method to imprint the fine points as well as the broad principles that can be gleaned in a clinical encounter. The originators of this book, Raymond D. Adams and Maurice Victor insisted that the basis of the practice of neurology necessarily differs from that of neuroscience in that neurology is a medical discipline and must always be related back to the patient. Here is the story:
A 19-year-old college sophomore began to show paranoid traits. She became convinced that her roommate was listening in on her phone conversations and planning to alter her essays. She became reclusive and spent most of her time locked in her room. After much difficulty, her
teachers convinced her to be seen by the student health service. It was believed she was beginning to show signs of schizophrenia and she was admitted to a psychiatric hospital, where she was started on antipsychotic medications. While in the hospital, she had a generalized seizure which prompted her transfer to our service. Her spinal fluid analysis showed 10 lymphocytes per mL3. She was found to have an anti-NMDA receptor antibody, which prompted an ultrasound examination of the pelvis. The left ovary was thought to show a benign cyst. Because of the neurological
syndrome, the ovarian cyst was resected and revealed a microscopic ovarian teratoma. The neuropsychiatric syndrome resolved. She has since graduated and obtained an advanced degree.
This class of disease, autoimmune encephalitis, appeared briefly in the last edition of this book, and not at all in the previous one, but has become a major field of modern neurology, now expanded to include antibodies to many other antigens, occurring de novo or in association with an array of tumors. What of the patients whose stories approximate this one but do not have one or two essential components? One wonders how many other patients harbor curious autoimmune disorders, which will be uncovered in future editions of Principles of Neurology.
The clinical features of conditions such as cerebral amyloid angiopathy, posterior reversible encephalopathy syndrome, the neuromyelitis optical spectrum, and toxicity of treatments such as adoptive cell therapy have all been expanded. The novel treatments now being applied to cerebrovascular disease, multiple sclerosis, muscular dystrophy, amyloidosis, and inborn enzyme deficiencies are among a list of triumphs of science that can only be applied by careful clinicians. In the present edition, there is hardly a category of disease that has not begun to yield to
the molecular biology and genetics.
Outside the laboratory, clinical trials have continued to build the background of information that applies to large groups of patients with neurological diseases. Clinicians are very aware, however, that the results of a trial have a less certain meaning for an individual patient. It is the skillful use of this information that this book aims to inform. Will the single patient be helped or harmed? Because medicine deals with the realities and complexities of illness, the clinician makes the best approximation of the correct course. The wise application of science, evidence from trials, and the traditional virtues of the neurological history and examination—essentially the craft of neurology—are the main purpose of
this edition of Principles of Neurology.
As has been our tradition, the book is written in a conversational style and we do not eschew stating our personal preferences when they are based on experience. We continue to find that readers value the uniformity of voice and approach of a few individual authors, rather than a discursive list of topics and writers. We thank Drs. Edward Stim, Mehrnaz Fallah, and Tim Lachman for invaluable assistance in proofreading the text.
For this edition, we introduce as a coauthor Dr. Sashank Prasad, a seasoned general neurologist with special training in neuro-ophthalmology and a director of our neurology training program. We hope that reading the ebook will feel akin to attending our ward rounds, clinics, or morning report, thus giving the reader an intimate window into demands of practice, without being prescriptive. We hope this edition allows the physician to use the material as a basis for continued professional growth and enjoyment. Welcome to our world.
Table of Contents:
PART 1: THE CLINICAL METHOD OF NEUROLOGY,
1 Approach to the Patient With Neurologic Disease,
2 Diagnostic Testing in Neurologic Disease,
PART 2: CARDINAL MANIFESTATIONS OF NEUROLOGIC DISEASE,
SECTION 1 Disorders of Motility,
3 Paralysis and Weakness,
4 Disorders of Movement and Posture,
5 Ataxia and Disorders of Cerebellar Function,
6 Disorders of Stance and Gait,
SECTION 2 Pain and Disorders of Somatic Sensation,
8 Disorders of Non-Painful Somatic Sensation,
9 Headache and Other Craniofacial Pains,
10 Pain in the Back, Neck, and Extremities,
SECTION 3 Disorders of the Special Senses,
11 Disorders of Smell and Taste,
12 Disturbances of Vision,
13 Disorders of Ocular Movement and Pupillary Function,
14 Deafness, Dizziness, and Disorders of Equilibrium,
SECTION 4 Epilepsy and Disorders of Consciousness,
15 Epilepsy and Other Seizure Disorders,
16 Coma and Related Disorders of Consciousness,
17 Faintness and Syncope,
18 Sleep and Its Abnormalities,
SECTION 5 Derangements of Intellect, Behavior, and Language Caused by Diffuse and Focal Cerebral Disease,
19 Delirium and the Other Acute Confusional States,
20 Dementia, the Amnesic Syndrome, and the Neurology of Intelligence and Memory,
21 Neurologic Disorders Caused by Lesions in Specific Parts of the Cerebrum,
22 Disorders of Speech and Language,
SECTION 6 Disorders of Energy, Mood, and Autonomic and Endocrine Functions,
23 Fatigue, Asthenia, Anxiety, and Depression,
24 The Limbic Lobes and the Neurology of Emotion,
25 Disorders of the Autonomic Nervous System, Respiration, and Swallowing,
26 The Hypothalamus and Neuroendocrine Disorders,
PART 4: MAJOR CATEGORIES OF NEUROLOGIC DISEASE,
29 Disturbances of Cerebrospinal Fluid, Including Hydrocephalus, Pseudotumor Cerebri, and Low-Pressure Syndromes,
30 Intracranial Neoplasms and Paraneoplastic Disorders,
31 Bacterial, Fungal, Spirochetal, and Parasitic Infections of the Nervous System,
32 Viral Infections of the Nervous System and Prion Diseases,
33 Stroke and Cerebrovascular Diseases,
34 Craniocerebral Trauma,
35 Multiple Sclerosis and Other Inflammatory Demyelinating Diseases,
36 Inherited Metabolic Diseases of the Nervous System,
37 Developmental Diseases of the Nervous System,
38 Degenerative Diseases of the Nervous System,
39 The Acquired Metabolic Disorders of the Nervous System,
40 Diseases of the Nervous System Caused by Nutritional Deficiency,
41 Disorders of the Nervous System Caused by Alcohol, Drugs, Toxins, and Chemical Agents,
PART 5: DISEASES OF SPINAL CORD, PERIPHERAL NERVE, AND MUSCLE,
42 Diseases of the Spinal Cord,
43 Diseases of the Peripheral Nerves,
44 Diseases of the Cranial Nerves,
45 Diseases of Muscle,
46 Disorders of the Neuromuscular Junction, Myotonias, and Persistent Muscle Fiber Activity,
PART 6: PSYCHIATRIC DISORDERS,
47 Anxiety Disorders, Hysteria, and Personality Disorders,
48 Depression and Bipolar Disease,
49 Schizophrenia, Delusional, and The paranoid States,
About the Author
Joshua P. Klein, MD, Ph.D. Chief, Division of Hospital Neurology; Clinical Service Director, Neurology; and Director of Performance Improvement, Neurology, Brigham and Women’s Hospital; and Associate Professor of Neurology and Radiology, Harvard Medical School.
Sashank Prasad, MD Chief, Division of Neuro-Ophthalmology and Associate Program Director, BWH-MGH Neurology Residency, Brigham and Women’s Hospital; and Associate Professor of Neurology, Harvard Medical School.
Reviews about of the customers about the textbook:
- Manish Patel:
Awesome book. Happy with it.
The definitive textbook on neurology, the one neurologists and neurosurgeons keep handy on their office bookshelf. Much more than the average person needs, but if you or someone in your family is diagnosed with a neurological syndrome, this is the place to look it up (I have used it in such situations many times).